Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells

Caenorhabditis elegans chaperonin CCT is required for the biogenesis of actin and tubulin and is thereby essential for microvillus formation in intestinal cells. Loss of CCT/TRiC had no strong effects on intermediate filament protein IFB-2 or cytoskeletal linker protein ERM-1, suggesting that CCT/TR...

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Bibliographic Details
Main Authors: Saegusa, Keiko, Sato, Miyuki, Sato, Katsuya, Nakajima-Shimada, Junko, Harada, Akihiro, Sato, Ken
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196862/