Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells

Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells

Hypoxia-induced cancer stem cells have been known to be involved in tumour metastasis, resistance to chemo/radio therapy and tumour recurrence. Magnetic Resonance Imaging is a widely used imaging tool for cancers in clinics and research. To develop T1-positive and T2-negative dual mode MRI agents fo...

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Bibliographic Details
Main Authors: Zhu, Haitao, Zhang, Lirong, Liu, Yanfang, Zhou, Yuepeng, Wang, Kang, Xie, Xiaodong, Song, Lian, Wang, Dongqing, Han, Chunlei, Chen, Qiuyun
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157021/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157021/

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