Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells

Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells

The initiation and progression of various solid tumors, including pancreatic carcinoma, are driven by a population of cells with stem cell properties, namely cancer stem cells (CSCs). Like their normal counterparts, CSCs are also believed to rely on their own microenvironment termed niches to sustai...

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Bibliographic Details
Main Authors: Zhu, Haitao, Wang, Dongqing, Liu, Yanfang, Su, Zhaoliang, Zhang, Lirong, Chen, Fangfang, Zhou, Yuepeng, Wu, Yingying, Yu, Ming, Zhang, Zhijian, Shao, Genbao
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177138/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177138/

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