Dysregulation of Bmi1 promotes malignant transformation of hepatic progenitor cells

Dysregulation of Bmi1 promotes malignant transformation of hepatic progenitor cells

Adult hepatic progenitor cells (HPCs) are involved in a wide range of human liver diseases, including hepatocellular carcinoma (HCC). Bmi1 has been reported to have vital roles in stem cell self-renewal and carcinogenesis. We have previously demonstrated that Bmi1 is upregulated in HCC with bile duc...

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Bibliographic Details
Main Authors: Zhang, R, Wu, W R, Shi, X D, Xu, L B, Zhu, M S, Zeng, H, Liu, C
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154353/

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