Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
JAK-STAT (Janus associated kinase-signal transducer and activator of transcription) pathway plays a critical role in transduction of extracellular signals from cytokines and growth factors involved in hematopoiesis, immune regulation, fertility, lactation, growth and embryogenesis. JAK family contai...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776247/ |