Targeted genome engineering in Caenorhabditis elegans

The generation of mutants and transgenes are indispensible for biomedical research. In the nematode Caenorhabditis elegans, a series of methods have been developed to introduce genome modifications, including random mutagenesis by chemical reagents, ionizing radiation and transposon insertion. In ad...

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Bibliographic Details
Main Authors: Chen, Xiangyang, Feng, Xuezhu, Guang, Shouhong
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146831/