Improved anti-leukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice

Despite the impressive clinical efficacy of T cells engineered to express chimeric antigen receptors (CAR-Ts), the current applications of CAR-T cell therapy are limited by major treatment-related toxicity. Thus, safer yet effective alternative approaches must be developed. In this study, we compare...

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Bibliographic Details
Main Authors: Liu, X, Barrett, D M, Jiang, S, Fang, C, Kalos, M, Grupp, S A, June, C H, Zhao, Y
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141353/