Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts

Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts

Bispecific antibodies (bsAbs) engaging T cells are emerging as a promising immunotherapeutic tool for the treatment of hematologic malignancies. Because their low molecular mass, bsAbs have short half-lives. To achieve clinical responses, they have to be infused into patients continously, for a long...

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Bibliographic Details
Main Authors: Aliperta, R, Cartellieri, M, Feldmann, A, Arndt, C, Koristka, S, Michalk, I, von Bonin, M, Ehninger, A, Bachmann, J, Ehninger, G, Bornhäuser, M, Bachmann, M P
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648523/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648523/

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