Oxidative guanine base damage regulates human telomerase activity

Oxidative guanine base damage regulates human telomerase activity

Changes in telomere length are associated with degenerative diseases and cancer. Oxidative stress and DNA damage have been linked to both positive and negative alterations in telomere length and integrity. Here we examined how the common oxidative lesion 8-oxo-7,8-dihydro-2′-deoxyguanine (8-oxoG) re...

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Bibliographic Details
Main Authors: Fouquerel, Elise, Lormand, Justin, Bose, Arindam, Lee, Hui-Ting, Kim, Grace S., Li, Jianfeng, Sobol, Robert W., Freudenthal, Bret D., Myong, Sua, Opresko, Patricia L.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140714/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140714/

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