Halogenated indoles eradicate bacterial persister cells and biofilms

The emergence of antibiotic resistance has necessitated new therapeutic approaches to combat recalcitrant bacterial infections. Persister cells, often found in biofilms, are metabolically dormant, and thus, are highly tolerant to all traditional antibiotics and represent a major drug resistance mech...

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Bibliographic Details
Main Authors: Lee, Jin-Hyung, Kim, Yong-Guy, Gwon, Giyeon, Wood, Thomas K., Lee, Jintae
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138170/