Metabolite-Enabled Eradication of Bacterial Persisters by Aminoglycosides

Bacterial persistence is a state in which a sub-population of dormant cells (persisters) tolerates antibiotic treatment1-4. Bacterial persisters have been implicated in biofilms and chronic and recurrent infections5-7. Despite this clinical relevance, there are currently no viable means for eradicat...

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Bibliographic Details
Main Authors: Allison, Kyle R., Brynildsen, Mark P., Collins, James J.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145328/