Optical imaging of MMP-12 active form in inflammation and aneurysm

Matrix metalloproteinase (MMP)-12 plays a key role in the development of aneurysm. Like other members of MMP family, MMP-12 is produced as a proenzyme, mainly by macrophages, and undergoes proteolytic activation to generate an active form. Accordingly, molecular imaging of the MMP-12 active form can...

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Bibliographic Details
Main Authors: Razavian, Mahmoud, Bordenave, Thomas, Georgiadis, Dimitris, Beau, Fabrice, Zhang, Jiasheng, Golestani, Reza, Toczek, Jakub, Jung, Jae-Joon, Ye, Yunpeng, Kim, Hye-Yeong, Han, Jinah, Dive, Vincent, Devel, Laurent, Sadeghi, Mehran M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137160/