Questions and controversies: the role of necroptosis in liver disease

Acute and chronic liver injury results in hepatocyte death and turnover. If injury becomes chronic, the continuous cell death and turnover leads to chronic inflammation, fibrosis and ultimately cirrhosis and hepatocellular carcinoma. Controlling liver cell death both in acute injury, to rescue the l...

Full description

Bibliographic Details
Main Authors: Dara, Lily, Liu, Zhang-Xu, Kaplowitz, Neil
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136616/