Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation

While transformation of normal cells to cancer cells is accompanied with a switch from oxidative phosphorylation (OXPHOS) to aerobic glycolysis, it is interesting to ask if cancer cells can revert from Warburg effect to OXPHOS. Our previous works suggested that cancer cells reverted to OXPHOS, when...

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Bibliographic Details
Main Authors: Wu, Hao, Ying, Minfeng, Hu, Xun
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130031/