The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer

Our objective was to evaluate the effect of the COX-2 inhibitor, celecoxib, on (1) proliferation and apoptosis in human ovarian cancer cell lines and primary cultures of ovarian cancer cells, and (2) inhibition of tumor growth in a genetically engineered mouse model of serous ovarian cancer under ob...

Full description

Bibliographic Details
Main Authors: Suri, Anuj, Sheng, Xiugui, Schuler, Kevin M., Zhong, Yan, Han, Xiaoyun, Jones, Hannah M., Gehrig, Paola A., Zhou, Chunxiao, Bae-Jump, Victoria L.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129955/