Everolimus exhibits anti-tumorigenic activity in obesity-induced ovarian cancer

Everolimus exhibits anti-tumorigenic activity in obesity-induced ovarian cancer

Everolimus inhibits mTOR kinase activity and its downstream targets by acting on mTORC1 and has anti-tumorigenic activity in ovarian cancer. Clinical and epidemiologic data find that obesity is associated with worse outcomes in ovarian cancer. In addition, obesity leads to hyperactivation of the mTO...

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Bibliographic Details
Main Authors: Guo, Hui, Zhong, Yan, Jackson, Amanda L., Clark, Leslie H., Kilgore, Josh, Zhang, Lu, Han, Jianjun, Sheng, Xiugui, Gilliam, Timothy P., Gehrig, Paola A., Zhou, Chunxiao, Bae, Victoria L.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991459/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991459/

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