Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians
Myostatin (MSTN) and α-actinin-3 (ACTN3) genes are potentially associated with preservation of muscle mass and oxidative capacity, respectively. To explore the possible role of these genes in exceptional longevity (EL), the allele/genotype frequency distribution of two polymorphisms in MSTN (rs18050...
Main Authors: | Fuku, Noriyuki, Alis, Rafael, Yvert, Thomas, Zempo, Hirofumi, Naito, Hisashi, Abe, Yukiko, Arai, Yasumichi, Murakami, Haruka, Miyachi, Motohiko, Pareja-Galeano, Helios, Emanuele, Enzo, Hirose, Nobuyoshi, Lucia, Alejandro |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755/ |
Similar Items
-
The mitochondrial‐derived peptide MOTS‐c: a player in exceptional longevity?
by: Fuku, Noriyuki, et al.
Published: (2015) -
Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795, and ACSL1 rs6552828
by: Fuku, Noriyuki, et al.
Published: (2015) -
Lack of replication of associations between multiple genetic polymorphisms and endurance athlete status in Japanese population
by: Yvert, Thomas, et al.
Published: (2016) -
Centenarianism
Published: (1905) -
Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research
by: Yagi, Takuya, et al.
Published: (2012)