The mitochondrial‐derived peptide MOTS‐c: a player in exceptional longevity?

Mitochondrial‐derived peptides (MDP) are encoded by functional short open reading frames in the mitochondrial DNA (mtDNA). These include humanin, and the recently discovered mitochondrial open reading frame of the 12S rRNA‐c (MOTS‐c). Although more research is needed, we suggest that the m.1382A>...

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Bibliographic Details
Main Authors: Fuku, Noriyuki, Pareja‐Galeano, Helios, Zempo, Hirofumi, Alis, Rafael, Arai, Yasumichi, Lucia, Alejandro, Hirose, Nobuyoshi
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693465/