TCR/pMHC Interaction: Phenotypic Model for an Unsolved Enigma

TCR–pMHC interaction is the keystone of the adaptive immune response. This process exhibits an impressive capacity of speed, sensitivity, and discrimination that allows detecting foreign pMHCs at very low concentration among much more abundant self-pMHC ligands. However, and despite over three decad...

Full description

Bibliographic Details
Main Authors: Gálvez, Jesús, Gálvez, Juan J., García-Peñarrubia, Pilar
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101211/