Force Measurements of TCR/pMHC Recognition at T Cell Surface

The rupture forces and adhesion frequencies of single recognition complexes between an affinity selected peptide/MHC complex and a TCR at a murine hybridoma surface were measured using Atomic Force Microscopy. When the CD8 coreceptor is absent, the adhesion frequency depends on the nature of the pep...

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Bibliographic Details
Main Authors: Puech, Pierre-Henri, Nevoltris, Damien, Robert, Philippe, Limozin, Laurent, Boyer, Claude, Bongrand, Pierre
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142151/