Pomegranate-Derived Polyphenols Reduce Reactive Oxygen Species Production via SIRT3-Mediated SOD2 Activation

Pomegranate-derived polyphenols are expected to prevent life-style related diseases. In this study, we evaluated the ability of 8 pomegranate-derived polyphenols, along with other polyphenols, to augment SIRT3, a mammalian SIR2 homolog localized in mitochondria. We established a system for screening...

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Bibliographic Details
Main Authors: Zhao, Chong, Sakaguchi, Takenori, Fujita, Kosuke, Ito, Hideyuki, Nishida, Norihisa, Nagatomo, Akifumi, Tanaka-Azuma, Yukimasa, Katakura, Yoshinori
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093269/