IRE1-Independent Gain Control of the Unfolded Protein Response

Nonconventional splicing of the gene encoding the Hac1p transcription activator regulates the unfolded protein response (UPR) in Saccharomyces cerevisiae. This simple on/off switch contrasts with a more complex circuitry in higher eukaryotes. Here we show that a heretofore unrecognized pathway opera...

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Bibliographic Details
Main Authors: Leber, Jess H, Bernales, Sebastián, Walter, Peter
Format: Online
Language:English
Published: Public Library of Science 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509300/