Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution

In an influential model of pattern formation, a gradient of Sonic hedgehog (Shh) signalling in the chick wing bud specifies cells with three antero-posterior positional values, which give rise to three morphologically different digits by a self-organizing mechanism with Turing-like properties. Howev...

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Bibliographic Details
Main Authors: Pickering, Joseph, Towers, Matthew
Format: Online
Language:English
Published: The Company of Biologists Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087615/