Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
Nicotinic acetylcholine receptors (nAChRs) are targets for developing new drugs to treat severe pain, nicotine addiction, Alzheimer disease, epilepsy, etc. α-Conotoxins are biologically and chemically diverse. With 12–19 residues and two disulfides, they can be specifically selected for different nA...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
MDPI
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082321/ |