AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

Neuronal nAChRs are a diverse family of pentameric ion channels with wide distribution throughout cells of the nervous and immune systems. However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack of selective probes. Here, we used a binding a...

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Bibliographic Details
Main Authors: Dutertre, Sébastien, Ulens, Chris, Büttner, Regina, Fish, Alexander, van Elk, René, Kendel, Yvonne, Hopping, Gene, Alewood, Paul F, Schroeder, Christina, Nicke, Annette, Smit, August B, Sixma, Titia K, Lewis, Richard J
Format: Online
Language:English
Published: Nature Publishing Group 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952216/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952216/

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