The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen® and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge

The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen® and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge

•Vaccination induces a pharyngeal antibody response in shorthorn zebu cross (SZC).•Direct challenge with the AlHV-1 virus is effective at inducing MCF in SZC.•Attenuated AlHV–1 + Emulsigen® vaccine efficacy in SZC calculated to be 50%.•Bacterial flagellin is not a good adjuvant as inclusion reduced...

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Bibliographic Details
Main Authors: Lankester, Felix, Lugelo, Ahmed, Werling, Dirk, Mnyambwa, Nicholas, Keyyu, Julius, Kazwala, Rudovick, Grant, Dawn, Smith, Sarah, Parameswaran, Nevi, Cleaveland, Sarah, Russell, George, Haig, David
Format: Online
Language:English
Published: Elsevier Scientific Pub. Co 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081063/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081063/

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