The Hv1 proton channel responds to mechanical stimuli

Hv1 is a voltage-gated proton channel that is composed of two voltage-sensing domains, each of which is permeable to protons. Pathak et al. find that these voltage-sensing domains are mechanosensitive and that membrane stretch results in a long-lived facilitation of Hv1 activation.

Bibliographic Details
Main Authors: Pathak, Medha M., Tran, Truc, Hong, Liang, Joós, Béla, Morris, Catherine E., Tombola, Francesco
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089936/