Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway

Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway

Twisted gastrulation (Tsg) and chordin are secreted glycoproteins that function together as BMP (bone morphogenetic protein) antagonists to regulate BMP growth factor signalling. Chordin binds to BMPs, preventing them from interacting with their receptors and Tsg is known to strengthen this inhibito...

Full description

Bibliographic Details
Main Authors: Troilo, Helen, Barrett, Anne L., Zuk, Alexandra V., Lockhart-Cairns, Michael P., Wohl, Alexander P., Bayley, Christopher P., Dajani, Rana, Tunnicliffe, Richard B., Green, Lewis, Jowitt, Thomas A., Sengle, Gerhard, Baldock, Clair
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080453/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080453/

Similar Items