Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development

Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development

Twisted gastrulation (TWSG1) is a conserved, secreted glycoprotein that modulates signaling of bone morphogenetic proteins (BMPs) in the extracellular space. Deletion of exon 4 of mouse Twsg1 (mTwsg1) is associated with significant craniofacial defects. However, little is understood about the bioche...

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Bibliographic Details
Main Authors: Billington, Charles J., Fiebig, Juliane E., Forsman, Cynthia L., Pham, Lan, Burbach, Nathan, Sun, Mu, Jaskoll, Tina, Mansky, Kim, Gopalakrishnan, Rajaram, O’Connor, Michael B., Mueller, Thomas D., Petryk, Anna
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170884/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170884/

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