Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling

Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling

Neutrophil release of NO/ONOO− induces endothelial cell barrier dysfunction in inflammatory acute lung injury (ALI). Previous studies using zymosan-triggered inflammation and ALI model revealed that zymosan promotes inducible NO synthase (iNOS) expression in neutrophils, and that isoflurane inhibits...

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Bibliographic Details
Main Authors: Li, Jun-Tang, Wang, Wei-Qi, Wang, Ling, Liu, Ning-Ning, Zhao, Ya-Li, Zhu, Xiao-Shan, Liu, Qin-Qin, Gao, Chun-Fang, Yang, An-Gang, Jia, Lin-Tao
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077975/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077975/

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