Subanesthetic Isoflurane Reduces Zymosan-Induced Inflammation in Murine Kupffer Cells by Inhibiting ROS-Activated p38 MAPK/NF-κB Signaling

Subanesthetic Isoflurane Reduces Zymosan-Induced Inflammation in Murine Kupffer Cells by Inhibiting ROS-Activated p38 MAPK/NF-κB Signaling

Volatile anesthetic isoflurane (ISO) has immunomodulatory effects. The fungal component zymosan (ZY) induces inflammation through toll-like receptor 2 or dectin-1 signaling. We investigated the molecular actions of subanesthetic (0.7%) ISO against ZY-induced inflammatory activation in murine Kupffer...

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Bibliographic Details
Main Authors: Wang, Hui, Wang, Lei, Li, Nan-lin, Li, Jun-tang, Yu, Feng, Zhao, Ya-li, Wang, Ling, Yi, Jun, Bian, Jie-fang, Chen, Jiang-hao, Yuan, Shi-fang, Wang, Ting, Lv, Yong-gang, Liu, Ning-ning, Zhu, Xiao-shan, Ling, Rui, Yun, Jun
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134815/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134815/

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