Wild-type p53 binds to MYC promoter G-quadruplex
We found that the p53 tumour suppressor protein binds specifically to the G-quadruplex DNA formed by MYC promoter sequence. We propose that p53 binding to G-quadruplexes can participate in regulation of p53 target genes.
| Main Authors: | , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064454/ |