Loss of loop adenines alters human telomere d[AG3(TTAG3)3] quadruplex folding

Loss of loop adenines alters human telomere d[AG3(TTAG3)3] quadruplex folding

Abasic (AP) lesions are the most frequent type of damages occurring in cellular DNA. Here we describe the conformational effects of AP sites substituted for 2′-deoxyadenosine in the first (ap7), second (ap13) or third (ap19) loop of the quadruplex formed in K+ by the human telomere DNA 5′-d[AG3(TTAG...

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Bibliographic Details
Main Authors: Babinský, Martin, Fiala, Radovan, Kejnovská, Iva, Bednářová, Klára, Marek, Radek, Sagi, Janos, Sklenář, Vladimír, Vorlíčková, Michaela
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267657/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267657/

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