Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) ins...

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Bibliographic Details
Main Authors: Hurtado-Roca, Yamilee, Ledesma, Marta, Gonzalez-Lazaro, Monica, Moreno-Loshuertos, Raquel, Fernandez-Silva, Patricio, Enriquez, Jose Antonio, Laclaustra, Martin
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063275/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063275/

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