Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

We recently introduced CDK5 as target in HCC, regulating DNA damage response. Based on this and on our previous knowledge about vascular effects of CDK5, we investigated the role of CDK5 in angiogenesis in HCC, one of the most vascularized tumors. We put a special focus on the transcription factor H...

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Bibliographic Details
Main Authors: Herzog, Julia, Ehrlich, Sandra M., Pfitzer, Lisa, Liebl, Johanna, Fröhlich, Thomas, Arnold, Georg J., Mikulits, Wolfgang, Haider, Christine, Vollmar, Angelika M., Zahler, Stefan
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053636/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053636/

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