Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial activity but lacked activity against human African trypanosomiasis. We have...
Main Authors: | Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel |
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Format: | Online |
Language: | English |
Published: |
Editions Scientifiques Elsevier
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049494/ |
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