Hypoxia-inducible factor-mediated induction of WISP-2 contributes to attenuated progression of breast cancer

Hypoxia and the hypoxia-inducible factor (HIF) signaling pathway trigger the expression of several genes involved in cancer progression and resistance to therapy. Transcriptionally active HIF-1 and HIF-2 regulate overlapping sets of target genes, and only few HIF-2 specific target genes are known so...

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Bibliographic Details
Main Authors: Fuady, Jerry H, Bordoli, Mattia R, Abreu-Rodríguez, Irene, Kristiansen, Glen, Hoogewijs, David, Stiehl, Daniel P, Wenger, Roland H
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045054/