Hypoxia-inducible factor-mediated induction of WISP-2 contributes to attenuated progression of breast cancer
Hypoxia and the hypoxia-inducible factor (HIF) signaling pathway trigger the expression of several genes involved in cancer progression and resistance to therapy. Transcriptionally active HIF-1 and HIF-2 regulate overlapping sets of target genes, and only few HIF-2 specific target genes are known so...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045054/ |