Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB

Two main features common to all solid tumors are tissue hypoxia and inflammation, both of which cause tumor progression, metastasis, therapy resistance and increased mortality. Chronic inflammation is associated with increased cancer risk, as demonstrated for inflammatory bowel disease patients deve...

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Bibliographic Details
Main Authors: Müller-Edenborn, Kamila, Léger, Karolin, Glaus Garzon, Jesus F., Oertli, Carole, Mirsaidi, Ali, Richards, Peter J., Rehrauer, Hubert, Spielmann, Patrick, Hoogewijs, David, Borsig, Lubor, Hottiger, Michael O., Wenger, Roland H.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653005/