Bacterial persistence is an active σS stress response to metabolic flux limitation

While persisters are a health threat due to their transient antibiotic tolerance, little is known about their phenotype and what actually causes persistence. Using a new method for persister generation and high‐throughput methods, we comprehensively mapped the molecular phenotype of Escherichia coli...

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Bibliographic Details
Main Authors: Radzikowski, Jakub Leszek, Vedelaar, Silke, Siegel, David, Ortega, Álvaro Dario, Schmidt, Alexander, Heinemann, Matthias
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043093/