The σ enigma: Bacterial σ factors, archaeal TFB and eukaryotic TFIIB are homologs

Structural comparisons of initiating RNA polymerase complexes and structure-based amino acid sequence alignments of general transcription initiation factors (eukaryotic TFIIB, archaeal TFB and bacterial σ factors) show that these proteins are homologs. TFIIB and TFB each have two-five-helix cyclin-l...

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Bibliographic Details
Main Authors: Burton, Samuel P, Burton, Zachary F
Format: Online
Language:English
Published: Taylor & Francis 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581349/