Unusual Salt and pH Induced Changes in Polyethylenimine Solutions

Linear PEI is a cationic polymer commonly used for complexing DNA into nanoparticles for cell-transfection and gene-therapy applications. The polymer has closely-spaced amines with weak-base protonation capacity, and a hydrophobic backbone that is kept unaggregated by intra-chain repulsion. As a res...

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Bibliographic Details
Main Authors: Curtis, Kimberly A., Miller, Danielle, Millard, Paul, Basu, Saswati, Horkay, Ferenc, Chandran, Preethi L
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042459/