‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7

‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7

Forkhead-associated (FHA) domains are phosphopeptide recognition modules found in many signaling proteins. The Saccharomyces cerevisiae protein kinase Rad53 is a key regulator of the DNA damage checkpoint and uses its two FHA domains to interact with multiple binding partners during the checkpoint r...

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Bibliographic Details
Main Authors: Almawi, Ahmad W., Matthews, Lindsay A., Larasati, Myrox, Polina, Boulton, Stephen, Lai, Christine, Moraes, Trevor, Melacini, Giuseppe, Ghirlando, Rodolfo, Duncker, Bernard P., Guarné, Alba
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041073/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041073/

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