Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment
Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment, but they also support robust sister chromatid cohesion at pericentromeres and facilitate replication of centromeric DNA early in S phase. Howe...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679449/ |