Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy

Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of...

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Main Authors:	Walter, Robert Fred Henry, Vollbrecht, Claudia, Werner, Robert, Mairinger, Thomas, Schmeller, Jan, Flom, Elena, Wohlschlaeger, Jeremias, Barbetakis, Nikolaos, Paliouras, Dimitrios, Chatzinikolaou, Fotios, Adamidis, Vasilis, Tsakiridis, Kosmas, Zarogoulidis, Paul, Trakada, Georgia, Christoph, Daniel Christian, Schmid, Kurt Werner, Mairinger, Fabian Dominik
Format:	Online
Language:	English
Published:	Ivyspring International Publisher 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039377/

id	pubmed-5039377
recordtype	oai_dc
spelling	pubmed-50393772016-10-03 Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy Walter, Robert Fred Henry Vollbrecht, Claudia Werner, Robert Mairinger, Thomas Schmeller, Jan Flom, Elena Wohlschlaeger, Jeremias Barbetakis, Nikolaos Paliouras, Dimitrios Chatzinikolaou, Fotios Adamidis, Vasilis Tsakiridis, Kosmas Zarogoulidis, Paul Trakada, Georgia Christoph, Daniel Christian Schmid, Kurt Werner Mairinger, Fabian Dominik Research Paper Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of platinum compounds remain largely unknown. Ivyspring International Publisher 2016-09-13 /pmc/articles/PMC5039377/ /pubmed/27698933 http://dx.doi.org/10.7150/jca.16390 Text en © Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See http://ivyspring.com/terms for terms and conditions.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Walter, Robert Fred Henry Vollbrecht, Claudia Werner, Robert Mairinger, Thomas Schmeller, Jan Flom, Elena Wohlschlaeger, Jeremias Barbetakis, Nikolaos Paliouras, Dimitrios Chatzinikolaou, Fotios Adamidis, Vasilis Tsakiridis, Kosmas Zarogoulidis, Paul Trakada, Georgia Christoph, Daniel Christian Schmid, Kurt Werner Mairinger, Fabian Dominik
spellingShingle	Walter, Robert Fred Henry Vollbrecht, Claudia Werner, Robert Mairinger, Thomas Schmeller, Jan Flom, Elena Wohlschlaeger, Jeremias Barbetakis, Nikolaos Paliouras, Dimitrios Chatzinikolaou, Fotios Adamidis, Vasilis Tsakiridis, Kosmas Zarogoulidis, Paul Trakada, Georgia Christoph, Daniel Christian Schmid, Kurt Werner Mairinger, Fabian Dominik Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
author_facet	Walter, Robert Fred Henry Vollbrecht, Claudia Werner, Robert Mairinger, Thomas Schmeller, Jan Flom, Elena Wohlschlaeger, Jeremias Barbetakis, Nikolaos Paliouras, Dimitrios Chatzinikolaou, Fotios Adamidis, Vasilis Tsakiridis, Kosmas Zarogoulidis, Paul Trakada, Georgia Christoph, Daniel Christian Schmid, Kurt Werner Mairinger, Fabian Dominik
author_sort	Walter, Robert Fred Henry
title	Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
title_short	Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
title_full	Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
title_fullStr	Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
title_full_unstemmed	Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy
title_sort	screening of pleural mesotheliomas for dna-damage repair players by digital gene expression analysis can enhance clinical management of patients receiving platin-based chemotherapy
description	Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of platinum compounds remain largely unknown.
publisher	Ivyspring International Publisher
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039377/
_version_	1613663254791323648

Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy

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