Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy

Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of...

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Bibliographic Details
Main Authors: Walter, Robert Fred Henry, Vollbrecht, Claudia, Werner, Robert, Mairinger, Thomas, Schmeller, Jan, Flom, Elena, Wohlschlaeger, Jeremias, Barbetakis, Nikolaos, Paliouras, Dimitrios, Chatzinikolaou, Fotios, Adamidis, Vasilis, Tsakiridis, Kosmas, Zarogoulidis, Paul, Trakada, Georgia, Christoph, Daniel Christian, Schmid, Kurt Werner, Mairinger, Fabian Dominik
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039377/