Insights into autophagosome biogenesis from in vitro reconstitutions
Macro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplasmic material in the lysosomal system. This is achieved by the sequestration of the cytoplasmic cargo material within double membrane-bound vesicles that fuse with lysosomes, wherein the vesicle’s inner membra...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Academic Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039013/ |