PI(5)P Regulates Autophagosome Biogenesis

PI(5)P Regulates Autophagosome Biogenesis

Phosphatidylinositol 3-phosphate (PI(3)P), the product of class III PI3K VPS34, recruits specific autophagic effectors, like WIPI2, during the initial steps of autophagosome biogenesis and thereby regulates canonical autophagy. However, mammalian cells can produce autophagosomes through enigmatic no...

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Bibliographic Details
Main Authors: Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306530/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306530/

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