Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS)

Protein turnover represents an important mechanism in the functioning of cells, with deregulated synthesis and degradation of proteins implicated in many diseased states. Therefore, proteomics strategies to measure turnover rates with high confidence are of vital importance to understanding many bio...

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Bibliographic Details
Main Authors: Holman, Stephen W., Hammond, Dean E., Simpson, Deborah M., Waters, John, Hurst, Jane L., Beynon, Robert J.
Format: Online
Language:English
Published: The Royal Society 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031629/