Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells

Despite aggressive chemoradiation (CRT) protocols in the treatment of patients with head and neck squamous cell carcinomas (HNSCC), the outcome is still unfavorable. To improve therapy efficacy we had already successfully tested the multikinase inhibitor sorafenib in combination with irradiation (IR...

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Bibliographic Details
Main Authors: Möckelmann, Nikolaus, Rieckmann, Thorsten, Busch, Chia-Jung, Becker, Benjamin, Gleißner, Lisa, Hoffer, Konstantin, Omniczynski, Maria, Steinmeister, Leonhard, Laban, Simon, Grénman, Reidar, Petersen, Cordula, Rothkamm, Kai, Dikomey, Ekkehard, Knecht, Rainald, Kriegs, Malte
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029646/