Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis

Enzymes have evolved with highly specific values of their catalytic parameters kcat and KM. This poses fundamental biological questions about the selection pressures responsible for evolutionary tuning of these parameters. Here we are address these questions for the enzyme adenylate kinase (Adk) in...

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Bibliographic Details
Main Authors: Tükenmez, Hasan, Magnussen, Helge Magnus, Kovermann, Michael, Byström, Anders, Wolf-Watz, Magnus
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028032/